Table of contents

Therapeutics

• Formoterol was more effective than terbutaline when taken as needed for moderate to severe asthma (1 July, 2001)
• Review: small treatment effect of disodium cromoglycate in childhood asthma is tempered by methodological flaws and publication bias (1 July, 2001)
• Review: antiplatelet drugs reduce pre-eclampsia, preterm birth, and stillbirth or neonatal death (1 July, 2001)
• Review: evidence is sparse and inconclusive for treating and monitoring chronic mild to moderate hypertension in pregnancy (1 July, 2001)
• Combination therapy with candesartan and lisinopril was more effective than monotherapy in type 2 diabetes and hypertension (1 July, 2001)
• Review: calcium antagonists lead to a higher risk for myocardial infarction, congestive heart failure, and major cardiovascular events (1 July, 2001)
• Review: ACE inhibitors, calcium antagonists, and more intensive blood pressure lowering strategies reduce cardiovascular events (1 July, 2001)
• Aspirin but not vitamin E prevented cardiovascular events in patients at risk (1 July, 2001)
• Rate and rhythm control showed similar symptom improvement in atrial fibrillation (1 July, 2001)
• Clopidogrel reduced recurrent ischaemic events in patients with previous cardiac surgery more than aspirin (1 July, 2001)
• Vitamin K lowered the international normalised ratio into the therapeutic range in patients receiving warfarin (1 July, 2001)
• Multicomponent comprehensive care was as effective as usual care for decreasing major bleeding in older patients on warfarin (1 July, 2001)
• Routine primary immunisation using a longer needle resulted in fewer local reactions in infants (1 July, 2001)
• Malaria prophylaxis with atovaquone-proguanil caused fewer gastrointestinal adverse events than chloroquine-proguanil (1 July, 2001)
• Psychological therapy reduced depression earlier (4 months) but at 1 year was not better than usual general practitioner care (1 July, 2001)
• Pseudoephedrine and acetaminophen relieved sinus symptoms in the course of the common cold (1 July, 2001)
• Ventilation tubes did not improve quality of life in persistent otitis media with effusion (1 July, 2001)
• Oedema reduction by mechanical compression improved the healing of foot infection in patients with diabetes mellitus (1 July, 2001)
• Review: evidence of the effectiveness of discharge planning is equivocal (1 July, 2001)
• Review: epidural or spinal anaesthesia reduces post-operative mortality and morbidity (1 July, 2001)