Footnotes

• Contributors AD and YM drafted the manuscript. JB analysed the data. AD, YM, JB, SR and RB all provided critical input on the final version of the manuscript.

• Funding Funding for the study described in this publication was provided by miDiagnostics. miDiagnostics is a private company created to develop a point-of-need diagnostic platform.

• Competing interests Johns Hopkins University holds a Board of Directors position in miDiagnostics, owns equity in the company and is also eligible to receive royalty payments for commercial sales by miDiagnostics. AD, JB, RB, SR and YM are eligible to receive distributions of royalty payments to JHU and/or payments related to JHU equity ownership interests in miDiagnostics. This arrangement has been reviewed and approved by the Johns Hopkins University in accordance with its conflict of interest policies.

• Ethics approval Johns Hopkins Medicine Institutional Review Board (approval number: IRB00122523).

• Provenance and peer review Not commissioned; externally peer reviewed.

• Data sharing statement There are no additional data beyond what is included in our original analysis.

• Patient consent for publication Not required.